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Prefilled Syringe (With Needle)

Prefilled Syringe (With Needle)

A prefilled glass syringe (PFS) allows injectable drugs to be delivered in a single step. Drawing up fluid from a vial into a disposable syringe, attaching a fresh needle to the syringe, and then administering the injection to the patient can be time-consuming. Prefilled glass syringes combine the functions of a pharmaceutical vial and a disposable syringe, saving time by reducing steps in the process.
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Description
Company Profile

 

ZCP is located in Chongqing City,China.Its Chinese full name is Chongqing Zhengchuan Pharmaceutical packaging Co., Ltd.ZCP specializes in the R&D and production of pharmaceutical tubular glass vials and caps almost 40 years.The company has four branch factories,intelligent stereoscopic warehouses,and over 2,000+employees. In the year of 2017,ZCP became the first private enterprise in pharmaceutical glass packaging field to be listed in the main stock market in China.

 

Why Choose Us

 

High Production Capacity
The company has four branch factories and three large-sized production bases, covering a land of more than 200,000 m2. The company has 8 furnaces to produce glass tubing and more than 600 sets of high-precision devices used for production of vials and caps.


Broad Market
Relying on its great production capacity and famous brand, Zhengchuan has established a nationwide sales service network and has established long-term friendly cooperation relations with more than four hundred customers in China, which makes the company enjoy a good reputation at home and abroad.
Our products sell well in several regions in the world, e.g. South America, Southeast Asia, Europe and Asia.

 

Wide Product Range
The company possesses a modern technology research & development center and an integrated manufacturing center of pharmaceutical glass tubing, glass vials and auxiliary caps. The company mainly produces various types of transparent and amber tubular glass injection vials, tubular glass oral liquid vials, tubular glass screwed-neck vials and ampoules.

 

Quality Assurance
All products would enter a closed warehouse directly from the workshop via mechanical automation, so as to eliminate pollution sources due to transport of products and entrance of staffs and reduce the percentage of pollution and damage of products.
All procedures are controlled by computer that connected with the Intranet of the company. It could realize the integration of management and control, achieve clear entry and stock out in warehouses, and eliminate the risks of wrong or mixed delivery of products.

 

Prefilled Syringe With Lure Lock 1ml Standrad Ready To Use

Prefilled Syringes ( With Luer Lock)

Specifications:1ml,1 ml ong,2ml,2.25ml,3ml. Glass Tube:Borosilicate tube.

Push Rod for Glass Pre-filled Syringe

Push Rod For Glass Pre-Filled Syringe

Customers can choose the push rod according to their needs.

1ml/2.25ml/3ml Medical Grade Class Pre-filled Syringe With Lure Lock Or Needle

Injection Boosters For Pre-Filled Syringe

The medical syringe booster can perform injection and pushing operations with its automatic control mechanism, which is safe, stable, and reliable.

Glass Empty Medical Grade Class Prefilled Syringe With Lure Lock Or Needle

Glass Empty Medical Grade Class Prefilled Syringe With Lure Lock Or Needle

ZCP's prefilled syringes (PFS) not only offer a highly stable, long-term storage solution for drugs, but also a safe and convenient delivery system for patients and clinicians.

product-629-800

2.25ml Prefilled Syringe With Luer Lock

1. Product:2.25ml glass prefilled syringe with luer lock
2. Material:Germany Schott 5.0 Neutral Borosilicate Glass,American West rubber stopper and Dow Corning silicone oil
3. Surface treatment: Silk screen printing.
4. MOQ:10000 pcs

PFS2

Prefilled Syringe (With Needle)

Specification:1ml long(with needle),Iml

 

What is Prefilled Syringe (With Needle)?

 

A prefilled glass syringe (PFS) allows injectable drugs to be delivered in a single step. Drawing up fluid from a vial into a disposable syringe, attaching a fresh needle to the syringe, and then administering the injection to the patient can be time-consuming. Prefilled glass syringes combine the functions of a pharmaceutical vial and a disposable syringe, saving time by reducing steps in the process.


While syringes have been used for many years, prefilled glass syringes are a relatively new development in pharmaceutical packaging and containment. A glass syringe is a small system consisting of a barrel, a plunger, a plunger rod, or a piston. The syringe may be supplied with a barrel cone and closure type that supports the attachment of a suitable needle later when the injection is administered.

 

Benefits of Prefilled Syringe (With Needle)
 

Increased Convenience
Convenience is one of the major benefits of prefilled syringes. These syringes save the time and effort of healthcare professionals as they do not have to fill the syringe with medicine manually. Moreover, prefilled syringes are easy to transport and can be stored easily. Patients also benefit from this convenience, as healthcare professionals can administer the syringe quickly without having to measure the dose or mix the medication with another solution.

 

Improved Safety
One of the most significant advantages of prefilled syringes is improved safety. The chances of medication errors are reduced when using a prefilled syringe. Healthcare professionals don't have to worry about over or under-dosing the patient, which is a common issue with traditional methods of medication delivery. They also do not have to worry about contamination or air bubbles, which reduces the risk of infection or other complications.

 

Accurate Dosing
Accuracy in dosage is vital in healthcare, and prefilled syringes offer more precision as compared to traditional delivery methods. Studies have shown that a prefilled syringe is more accurate in dosing medication compared to the vial and ampoules methods. With prefilled syringes, patients get an accurate dose of medication which in turn leads to better health outcomes.

 

Cost-Effective
Although there is a higher initial cost than traditional delivery methods, prefilled syringes are cost-effective in the long run. They reduce the need to order additional components, and there are fewer disposal costs associated with these syringes. Additionally, patients benefit as they require fewer visits to the healthcare provider, reducing costs associated with healthcare overall.

 

How to Ensure The Safety of Drugs With Prefilled Syringe (With Needle)

The pre-filled syringe is a specialized packaging for pharmaceuticals that plays a crucial role in the transportation and storage of medications, while also serving as a means of administration. To ensure the safety of the medication, pre-filled syringes are composed of multiple components, each with its own specific function.

 

Firstly, the choice of packaging materials is of utmost importance. These materials must meet quality standards and possess non-toxic and odorless characteristics. Typically, pre-filled syringes are made from polyethylene or polypropylene, which are non-toxic, odorless, and offer excellent barrier properties, effectively preventing the ingress of external moisture and impurities.

 

Secondly, the sealing integrity of the packaging is crucial. The sealing of pre-filled syringes is primarily achieved through the cap and plunger. The cap ensures the sealing of the needle portion, while the plunger ensures the sealing of the barrel.

 

To ensure the proper storage of medications within pre-filled syringes, attention must be given to the choice of packaging materials and sealing integrity. Selecting appropriate packaging materials and ensuring good sealing integrity are essential to guarantee the safety and stability of the medication throughout its shelf life.

 

 

Prefilled Syringe (With Needle) Performance And Why Siliconization Matters

 

While the most conventional form of injectable drug delivery involves the classic combination of a vial and a hypodermic needle, more recent innovations have advanced the parenteral administration of APIs. Most notably, prefilled syringes have become a very popular method of drug delivery in the past few decades. With a prefilled syringe, the process of administering a drug product can be safer, quicker and easier for nurses and patients.

 

The prefilled nature of these syringes means nurses or patients are not required to prepare and draw the medicine into the needle, as the correct amount is already present in the barrel ready for quick injection. This creates less room for preparation and dosing errors when compared to vials and enables a more efficient drug delivery process.

 

Performance requirements
Prefilled syringes have four key components: a plunger, stopper, barrel, and a needle. In order for the mechanism to function properly, the plunger and stopper must fit tightly inside of the barrel but should glide through it when pressure is applied. Problems can sometimes arise due to the slightly tacky surface of elastomer stoppers, which have a tendency to create friction against the barrel surface.

 

The amount of pressure it takes to break the static friction of the plunger is known as the break-loose force. If this force is too high, the syringe becomes less and less easy to use, making it more difficult to administer the medicine and creating a less comfortable experience for the patient.

 

Once the break-loose force has been overcome, delivering the API in a single, smooth push is also key to good patient experiences. This is known as the glide force and should be as continuous as possible. In particular, syringe drivers – small, battery-operated devices used to subcutaneously deliver medicines to palliative care patients at a constant rate – require consistent glide forces to function effectively.

 

Production Of Prefilled Syringe (With Needle)

 

 

The production and the filling of prefilled syringes is a process that comprises a lot of single steps: first the syringe has to be manufactured out of glass tubes. After that the syringes have to be cleaned, sterilized and siliconized. Different processes are requested if the syringes are used as prefilled syringes in the nest or as "bulk" syringes. The single drugs or serum require different filling methods depending on the physical, chemical or pharmaceutical characteristics. When closing the syringe with a stopper not only the filled substance but also the used materials and coatings have to be considered. The article reflects the different technical aspects and especially works on the critical point in the process.

 

The theme prefilled syringes and the collateral technical aspects during the production are comprehensive. The choice of the appropriate processes and equipment for filling, siliconization, sterilization, closing and filling of the syringes can only be made after an extensive discussion of all relevant factors and often only after carrying out tests. Longtime know-how and a lot of experience with the different products are necessary. Only by this the ideal interaction between equipment, packaging components and product can be selected.

 

Prefilled Syringe (With Needle) Assembly and Packaging

 

Patients receiving injectable treatments for chronic diseases, allergies and a number of other therapies critical to health have benefitted from patient convenient dosage forms. The use of pre-filled syringes, auto-injectors and pen injectors has enabled safe and effective self-injection. The devices are simple to use and precise, performing reliably and reproducibly.

 

Pre-filled syringe processing must assemble syringe components ensuring sterility / maintenance of sterility and ensuring maintenance of syringe performance within the set parameters.. This means the process development starting from design to manufacturing is very demanding. Every element must be accurately placed, assembled and packaged.

 

Compliant facilities are supported by experienced and knowledgeable personnel along with the cutting-edge machinery necessary to provide the highest quality assembly solutions from conception to finished market goods. Our capacity is expanding and we are always prepared to set up efficient, cost-effective assembly lines for our customers. SteriPack performs end-to-end testing to ensure specifications are met, high performance and much more. We share expertise and ideas from small to large-scale production to increase optimization of the assembly process and find the most competitive solutions.

 

With every project we consider number of product presentations, annual batch size and device complexity. All processes take place in cGMP compliant clean room. Assembly solutions are developed from conception to finished market goods, our proven track record of setting up customized assembly lines covers manual, semi-automated and automated production.

 

How to use a Prefilled Syringe (With Needle) Correctly

 

The steps to use a Prefilled Syringe (With Needle) correctly include checking the packaging, syringe assembly, cleaning hands, taking the medicine, cleaning the injection site, pushing the needle, injecting the medicine, and disposing of waste.

 

1. Check the packaging: Before using the Prefilled Syringe (With Needle), confirm that the syringe packaging is intact and check the expiration date of the medicine to ensure the effectiveness of the medicine.

 

2. Syringe assembly: Open the package and install the needle correctly on the prefilled flush syringe according to the instructions. Make sure that the connection between the needle and the syringe is tight and secure to prevent drug leakage or dripping.

 

3. Clean your hands: Wash your hands thoroughly with soap and water to ensure that your hands are clean and disinfected. This can reduce the risk of cross-infection to the patient.

 

4. Take the medicine: Insert the needle into the medicine bottle and make sure that the needle and the medicine bottle fit well. Slowly and steadily draw the required amount of medicine into the syringe. Avoid air entering the syringe to reduce the generation of bubbles.

 

5. Clean the injection site: Use iodine cotton balls to wipe the patient's injection site to prevent infection. Move in a circular motion from the center of the injection site outward, making sure the entire area is thoroughly cleaned and disinfected.

 

6. Push the needle: Hold the syringe lightly and quickly but steadily penetrate the patient's skin. Avoid lingering on the skin surface for a long time to reduce pain and discomfort.

 

7. Inject the drug: Inject the drug slowly to ensure that the drug enters the patient's body at an appropriate speed. During the injection process, pay attention to the patient's reaction. If discomfort or abnormality occurs, please stop the injection in time and consult a medical staff.

 

8. Dispose of waste: After the injection is completed, remove the needle and discard the prefilled flush syringe and needle according to the disposal method of medical waste. Put it in a dedicated medical waste container to avoid accidental injury or infection to others.

 

Our Factory

Our company is the first to build a 3d warehouse in the same industry in China, mechanical automation closed warehouse, dust free storage, reducing the risk of mis-sending and mixing.

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productcate-780-540

 

Certificate

productcate-1-1

 

FAQ

Q: What is a prefilled syringe used for?

A: A PFS is a presentation of one or more active medicines, at the required concentration and volume, in the final syringe and ready for parenteral administration to the patient. PFS are intended to reduce error and minimise the time taken to prepare parenteral medicine by staff in clinical areas.

Q: Are pre-filled syringes single use?

A: Pre-filled syringes offer unparalleled convenience for patients and healthcare providers. Because the pre-filled syringe is a single-use device, there are no concerns about reuse or contamination.

Q: What are the advantages of pre-filled syringes?

A: A prefilled syringe system generates fewer particles during drug administration, as compared to a vial containment system. Furthermore, this form of drug delivery system ensures efficiency and greater convenience.

Q: What is the difference between prefilled syringe and cartridge?

A: Prefilled syringes have a set volume and concentration of contrast agent in a power injector-compatible syringe. They are considerably easier to use than bottle-filled cartridges and reduce the possibility of contamination or misadministration.

Q: How long can you keep a prefilled syringe?

A: If you prefill syringes: Store the prefilled syringes in the refrigerator with the needle pointing up to prevent insulin from blocking the needle opening. Syringes filled with one type of insulin (rather than mixed insulin) will keep for about a month.

Q: What is the purpose of a prefilled syringe?

A: Medical devices such as auto-injectors are increasingly used to help patients manage their own injection schedules for chronic conditions or other repeat dosing scenarios. Many auto-injectors rely on a prefilled glass syringe for drug containment and delivery.

Q: What is the difference between vial and prefilled syringe?

A: Prefilled Syringes offer greater time-saving efficiencies as they require no further processing steps before being taken to the fill line, in comparison to the washing-depyrogenation processes required for glass vials.

Q: What is the standard for prefilled syringes?

A: ISO 11040 is a testing standard that addresses the design and functional properties of prefilled syringes. ISO 11040 is used primarily within the pharmaceutical industry and is critical for ensuring that syringes work properly in a clinical setting.

Q: How are prefilled syringes packaged?

A: For prefilled syringes, plastic or glass syringes are the primary packaging devices. Secondary packaging - These are products such as clamshells, lidding, ready-to-use tubs, cartons, and thermoformed trays that protect the primary packaging devices and exhibit your product to the end consumers.

Q: How do you store prefilled syringes?

A: If you prefill syringes: Store the prefilled syringes in the refrigerator with the needle pointing up to prevent insulin from blocking the needle opening. Syringes filled with one type of insulin (rather than mixed insulin) will keep for about a month.

Q: How long does a prefilled syringe remain sterile?

A: Prefilled insulin syringes that are prepared by nurses using good aseptic technique and are stored in the patient's refrigerator appear to remain sterile for up to one month after preparation.

Q: What is the purpose of a prefilled syringe?

A: Medical devices such as auto-injectors are increasingly used to help patients manage their own injection schedules for chronic conditions or other repeat dosing scenarios. Many auto-injectors rely on a prefilled glass syringe for drug containment and delivery.

Q: What are the advantages and disadvantages of prefilled syringes?

A: Eliminating dosing errors and ease of use are two of the greatest advantages of pre-filled syringes. However, there are a number of challenges that manufacturers face, such as the interaction between the pre-filled syringes and the drug, stability concerns, and quality control.

Q: How long can you keep a prefilled syringe?

A: If you prefill syringes: Store the prefilled syringes in the refrigerator with the needle pointing up to prevent insulin from blocking the needle opening. Syringes filled with one type of insulin (rather than mixed insulin) will keep for about a month.

Q: What is the difference between pre-filled syringe and cartridge?

A: Prefilled syringes have a set volume and concentration of contrast agent in a power injector-compatible syringe. They are considerably easier to use than bottle-filled cartridges and reduce the possibility of contamination or misadministration.

Q: 16.3What does pre-filled syringe mean?

A: A pre-filled syringe is a disposable syringe that is supplied already loaded with the substance to be injected. The solution is supplied as a pre-filled syringe already containing the liquid for injection. A pre-filled syringe is a single dose of medication to which a needle has been fixed by the manufacturer.

Q: What are the different types of prefilled syringes?

A: A prefilled syringe commonly consists of the glass syringe, plunger, needle shield (soft or rigid), and plunger rod, and may also be incorporated into an autoinjector or medical device. For the purposes of this article, the focus will be on the terminology and designs of plunger and glass syringe.

Q: How do you administer a prefilled syringe?

A: Hold the syringe like a pencil and quickly insert the needle through the skin. Slowly push the plunger all the way down into the syringe. Release the pinch of skin slowly, then pull the needle out of the skin. Some medicines, like Stelara, come in syringes that automatically cover the needle.

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