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Glass Vials

Your Professional Pharmaceutical Glass Vials Manufacturer

 

 

Chongqing Zhengchuan Pharmaceutical Packaging Co., Ltd. is an enterprise that is professionally engaged in research, development, and production of pharmaceutical tubular glass vials and caps. Our products include: Pharmaceutical Glass Vials, Ampoule, Glass Tube, Vial Cap, Pre-filled Syringe, Rubber Stopper, Bottle Screen Printing, Irregular Shape Bottle, Cosmetic Bottle.

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Why Choose Us
 
 
High Production Capacity

The company has four branch factories and three large-sized production bases, covering a land of more than 200,000 m2. The company has 8 furnaces to produce glass tubing and more than 600 sets of high-precision devices used for production of vials and caps.

 
Broad Market

(1)Relying on its great production capacity and famous brand.

(2)Zhengchuan has established a nationwide sales service network and has established long-term friendly cooperation relations with more than four hundred customers in China, which makes the company enjoy a good reputation at home and abroad.
(3)Our products sell well in several regions in the world, e.g. South America, Southeast Asia, Europe and Asia.

 
Wide Product Range

The company possesses a modern technology research & development center and an integrated manufacturing center of pharmaceutical glass tubing, glass vials and auxiliary caps. The company mainly produces various types of transparent and amber tubular glass injection vials, tubular glass oral liquid vials, tubular glass screwed-neck vials and ampoules.

 
Quality Assurance

(1)All products would enter a closed warehouse directly from the workshop via mechanical automation, so as to eliminate pollution sources due to transport of products and entrance of staffs and reduce the percentage of pollution and damage of products.
(2)All procedures are controlled by computer that connected with the Intranet of the company. It could realize the integration of management and control, achieve clear entry and stock out in warehouses, and eliminate the risks of wrong or mixed delivery of products.

 

 

 

What is Pharmaceutical Glass Vials

We've applied our expertise in glass science, optical physics, vapor deposition, precision forming, and extrusion to design and develop a Pharmaceutical Glass Vials container to protect drugs and vaccines. Pharmaceutical Glass Vials enhances the storage and delivery of drugs, providing more reliable access to medicines essential to public health.

25ml Amber Low Borosilicate Glass Oral Liquid Vials

 

Benefits of Pharmaceutical Glass Vials
Temperature Resistant It's extremely important that pharmaceuticals are kept at their optimal temperature, as any slight change can affect the medicine's properties. Glass packaging is fantastic at regulating the temperature of products, as it doesn't react to changing temperatures by losing structure or leaking chemicals.
Non-Reactive to Chemicals Glass is a strong non-reactive material, meaning that it it will not leak any matter into the liquid within any glass container. This feature is of course especially important for pharmaceuticals, as medicines are comprised of delicate balances of elements to create the correct mixture that will treat the patient. If anything is leaked into this fine balance, then it is likely that the medicine would not be as effective.
Doesn't Leak or Seep Some types of plastic can leak Bisphenol A (BPA), which is a chemical found in many types of plastic, that is thought could cause possible ill health effects to the brain and blood pressure when ingested. Although this fear is yet to be conclusively proved by science, if you have any doubts about using plastic to package your pharmaceuticals, then you need to opt for glass packaging for pharmaceuticals.
Can be Easily Sterilised Sterilising glass is so easy because it can hold structure when exposed to high boiling temperatures, making it simple to kill off any harmful bacteria and germs. Glass can also be baked afterwards to dry it a controlled way and it won't crack!

 

Features of Pharmaceutical Glass Vials
1. Eliminates Delamination

Pharmaceutical Glass Vials is chemically durable with uniform surface chemistry that eliminates risk of delamination

2. Resists Damage and Breakage

Pharmaceutical Glass Vials is exceptionally strong to protect valuable drugs and reduce downtime due to glass-related interventions.

3. Prevents Cracks

Vial damage on commercial filling lines can create sub-visible cracks that can compromise drug sterility. In laboratory testing, Pharmaceutical Glass Vials provided at least 30% protection against cracks versus conventional borosilicate glass vials.

4. Reduces Glass Particulate Generation

Pharmaceutical Glass Vials have a low coefficient of friction exterior surface that reduces particulate generation on commercial filling lines. ​

5. Enhanced Performance

Zhengchuan's proprietary low coefficient-of-friction coating on Pharmaceutical Glass Vials enables higher line speeds and reduces the need for intervention due to vial jams, tip overs and glass breakage. Pharmaceutical Glass Vials can improve filling line efficiency by up to 50% compared to conventional borosilicate vials.

 

Common Types of Pharmaceutical Glass Vials

Type I Glass

Also known as "neutral," type 1 is a borosilicate glass with good chemical resistance. It is used for pharmaceuticals requiring the least reactive containers.
Typical Type I products:
Tubular glass vials
Pre-fillable syringes
Cartridges

Type II Glass

A treatment applied to the internal surface of the glass reduces ion exchange, making this category suitable for solutions administered intravenously.
Typical Type II products:
Moulded glass infusion bottles

Type III Glass

This is a soda-lime glass and is the type most commonly manufactured.
Typical Type III products:
Moulded glass syrup bottles
Tablet containers

 

Applications of Pharmaceutical Glass Vials

 

 

Pharmaceutical Borosilicate Glass Vials

Blood and Blood Components

Plasma, platelets, red blood cells, white blood cells, immunoglobulins, albumin and more are highly valuable for treating numerous diseases and protecting health.

Pharmaceutical Borosilicate Glass Vials

Oncology

Drug stability and sterility are crucial for patient safety. The mechanical resistance of molded glass is particularly important to ensure the integrity of cytotoxic cancer therapies.

Pharmaceutical Borosilicate Glass Vials

Antibiotics

Flexibility, integrity, and cost are essential features of glass packaging for the antibiotic supply chain – all met by our extensive Type I molded glass range of vials and infusion bottles.

Clear Low Borosilicate Glass Tube Vial for Injection

Respiratory

Type I glass is a popular packaging option for respiratory therapies, notably for nasal drug products and parenteral vials, owing to its superior mechanical resistance.

 

Process of Pharmaceutical Glass Vials
 

Melting The raw material, consisting of a mix of silica sand, soda ash and other components, is collected in silos, then dosed, mixed and fed into the furnace to be melted. The furnace, constructed of refractory material capable of withstanding the high melting temperatures (1,600°C), is connected to monitors and process calculators that allow the operating parameters to be constantly checked with the correct vitrification of raw materials.

 

Shaping The molten glass enters thermal conditioning channels and, having reached the appropriate viscosity, is 'cut' into drops. The glowing glass droplet drops into the mould on the moulding machine, which then moulds the finished product using two different moulding technologies. The "blow-blow" technique relies on an initial blowing stage to create a vacuum in the preform, which is then shaped by another jet of air and assumes its final shape. By contrast, the "die-blowing" technique uses a piston to create a vacuum in the preform, which is then blown to its final shape.

 

Annealing The phase that eliminates residual stresses in the material, stabilising the structure of the glass and increasing its strength. Other secondary treatments are also applied. such as siliconizing and sulfurization, which improve the performance of the products, and make them more resistant to mechanical and chemical stresses, and more suitable for in-line processing.

 

Certificate

 

Our company has worked out a set of perfect quality control system, among those from our competitors which is the first one that is ISO9002 and ISO9001:2008 certified successfully.
Our products are kept on the DMF record by FDA:
DMF Number Assigned:21564.
Low-borosilicate glass tubular injection vials: DMF Number Assigned: 21564
DMF Number Assigned:21565.
Neutral-borosilicate glass tubular injection vials: DMF Number Assigned: 21565

 

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Our Factory

 

Our company is the first to build a 3d warehouse in the same industry in China, mechanical automation closed warehouse, dust free storage, reducing the risk of mis-sending and mixing.

 

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Frequently Asked Questions

Q: Why Do Glass Vials Matter?

A: Over the past few decades, significant progress has been made in the biopharmaceutical industry with advancements in biological drugs, filling lines, and drug delivery systems. However, the glass vials used to contain these drug products have remained largely unchanged since the introduction of borosilicate glass vials over 100 years ago. Traditional borosilicate glass vials are susceptible to quality issues, such as cosmetic defects, vial damage and glass particles that are generated in fill-finish operations. Additionally, borosilicate glass can delaminate on the drug-contact surface. Issues like delamination, glass particles, and cracked containers have led to drug recalls and pose a threat to drug product sterility.

Q: What are the properties of Pharmaceutical Glass Vials?

A: Clarity: A glass vial features a smooth, clear surface, which allows you to inspect the contents for contamination or degradation. This is one of the reasons glass is the recommended container material for injectable liquids. Inertness: Borosilicate glass will not react with other substances, except for a few acids.

Q: What is a pharmaceutical vial?

A: Vials are small bottles or containers made from either plastic or glass. They're used to store medicines in liquid form, and they can even store powders or tablets.

Q: What are the components of bottle glass?

A: Silica (sand), soda ash, limestone, and cullet (furnace-ready, recycled glass) are combined into a specific mixture based on the desired properties of the bottle. The mixture is then melted at high temperatures in the furnace until it becomes a molten material, ready for formation.

Q: What are the different types of medicine vials?

A: There are several different types of commonly used closure systems. For glass vials, options include screw vials (closed with a screw cap or dropper/pipette), lip vials (closed with a cork or plastic stopper) and crimp vials (closed with a rubber stopper and a metal cap).

Q: What is a Type 1 glass vial?

A: Also known as "neutral," type 1 is a borosilicate glass with good chemical resistance. It is used for pharmaceuticals requiring the least reactive containers.

Q: What are Pharmaceutical Glass Vials used for?

A: Pharmaceutical Glass Vials have various sizes and shapes for different uses such as storing pharmaceutical liquids, powders, or capsules. Both clear and amber glass vials are available. Clear glass vial is suitable for most pharmaceuticals with a high ultraviolet transmission. Clear glass vial is suitable for most pharmaceuticals due to high ultraviolet transmission. However, for light-sensitive medicines, amber glass vial is highly recommended as it can absorb the higher-energy part of the visible spectrum and extend the shelf lives of drugs significantly.

Q: What types of Pharmaceutical Glass Vials are there?

A: Injection vials
Material:
Body: low borosilicate glass, neutral borosilicate glass, high borosilicate glass and soda lime
Cap: rubber stoppers, aluminum caps, aluminum plastic caps or upon request
Color: clear and amber
Shape: tubular
Neck finish: crimp top
Capacity: 2 ml, 3 ml, 5 ml, 7 ml, 8 ml, 10 ml, 15 ml, 20 ml, 30 ml or upon request
Surface handling: screen printing, bronzing, spraying or upon request.
Oral solution vials
Material:
Body: low borosilicate glass, neutral borosilicate glass, high borosilicate glass and soda lime
Cap: rubber stoppers, aluminum caps, aluminum plastic cap or upon request
Color: clear and amber
Shape: tubular
Neck finish: screw top, crimp top.
Capacity: 6 ml, 10 ml, 15 ml, 20 ml or upon request.
Surface handling: screen printing, bronzing, spraying or upon request.
Sample vials
Material:
Body: low borosilicate glass, neutral borosilicate glass, high borosilicate glass and soda lime
Cap: plastic caps, rubber stoppers, aluminum caps, aluminum plastic caps or upon request
Color: clear and amber
Shape: tubular
Neck finish: screw top
Capacity: 2 ml, 4 ml, 6 ml, 8 ml, 12 ml, 16 ml or upon request
Surface handling: screen printing, bronzing, spraying or upon request.
Glass ampoules
Material: low borosilicate glass, neutral borosilicate glass, high borosilicate glass and soda lime
Color: clear and amber
Capacity: 1 ml, 2 ml, 3 ml, 5 ml, 10 ml, 20 ml, 25 ml, 30 ml or upon request
Surface handling: screen printing, bronzing, spraying or upon request.

Q: What are the benefits of Pharmaceutical Glass Vials for pharmaceuticals?

A: Glass jars prove a popular choice in pharma, meeting strict industry demands without compromising on style or aesthetic appeal. Here, we break down the key qualities driving demand for glass jars in pharma.
Environmentally friendly
Glass jars are an environmentally friendly choice when it comes to pharmaceutical packaging. Not only can glass jars be sterilised for reuse but glass is also widely recycled to avoid waste.
Compliant
Many glass jars comply with the strict regulations placed on pharmaceutical packaging – for example, Drug Master Files of the US Food and Drug
Administration regulations, the British Standard BS1679 required for containers for pharmaceutical dispensing and the US and EU light transmission requirements.
Leak-proof
Unlike some alternative pharmaceutical packaging materials – such as some types of plastic – glass is completely leak-proof. This provides peace of mind that potentially harmful substances won’t permeate the packaging and keeps products safe from contamination.
Temperature- and chemical-resistant
Glass jars can not only withstand high temperatures but are also non-reactive to chemicals. This makes them the perfect choice for use with a range of medicines and pharmaceutical products – maintaining structural integrity regardless of contents and delivering medicines exactly as intended.
Plus, as the jars can withstand high temperatures, it means they can be easily sterilised – a critical quality in pharma, killing harmful germs and bacteria.
Coloured glass
Glass jars are often available in a range of colours – including clear, amber, green and blue – each with a unique appeal. Amber glass is designed to protect products from harmful UV light, while blue and green glass provides eye-catching aesthetic appeal and clear glass allows consumers to see the product through the packaging on store shelves.

We're well-known as one of the leading glass vials manufacturers and suppliers in China. If you're going to buy high quality glass vials, welcome to get more information from our factory. Also, customized service is available.

Neutral Borosilicate Glass Injection Ampoules, Low Borosilicate Oral Liquid Vials, Soda-lime Glass Tubes

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