The Prefillable Syringe Product Status
At present，there are two types of prefillable syringes on the market glass material and polymer material(COP). In2020，many foreign companies including the United States and Japan wil apply to China for filing and registration of polymer material prefillable syringe products. Up to now.the official website of the Center for Drug Evaluaion of the National Medical Products Administration has shown that only Shandong Ujoin Medcal Technology Co，Ltd.has transferred the product“A' from the evaluation of the association between polymer preflllable syringe and medicals.
COP is an amorphous transparent polymer materialwith acyclic stucture，which is a kind of cyclic hydrocarbon with carbon-carbon double bond in the ring. COC is a polymer obtained by hydrogenating the unsaturated double bond of norbornene monomer after ring-opening metathesis polymerization.
COP materials have many advantages over glass materials：high glass transtion temperature(can withstandhigh temperatures terization) ，good optical performance(high transparency，low birefringence) ，strong gas barrier properties(O2， H2O、CO2、N2) ， wide application range(chemical resistance，acid and alkali resistance，scratch resistance) . It has low protein adsorption and no heavy metal residues， can achieve silicon-free injection， has good biocompatibility and high medical safety. It can realize multi-cavity high-efficiency injection molding， large-scalemanufacturing， high production efficiency， stable quality，and no damage during production，transportation and use. COP prefillable syringes are the best supplement and replacement product for glass prefillable syringes.
